いつも時代の一歩前へ

東京医科歯科大学で講演した内容
日本語解説　　　　　　　　　１．とても少ない精子に対する精子調整方法２．精子の凍結保存　　　（１）透明帯内精子凍結保存　　　（２）クライオトップを使った精子凍結保存３．乏精子-精子無力症に対する治療　　　乏精子-精子無力症に対するFSH製剤治療４．レスキューICSI ５．受精障害（卵活性化の失敗）　　　卵細胞質の吸引６．胚の質（胚のフラグメンテーション）　　　frag処理７．アシステッドハッチング　　　酸性タイロードによるアシステッドハッチング　　　レーザーによるアシステッドハッチング８．透明帯のない卵９．更なる研究　　　（１）体外成熟　　　（２）胚と子宮内膜の共培養　　　（３）電気刺激　　　（４）カルシウムイオノフォア
当院スタッフは日本産婦人科学会関東連合から学術奨励賞を授与されています。また、その他の研究で世界体外受精会議記念賞候補となりました。アメリカやヨーロッパの医学雑誌に掲載された当院スタッフの研究たち
. Hoshimoto K, Ohta Y, Ohkura T, Inaba N. 　Changes in plasma soluble CD26 and CD30 during pregnancy : markers of Th1/Th2 balance? 　Gynecol Obstet Invest 50(4) : 260-263, 2000. 2. Hoshimoto K, Hayashi M, Ohkura T. 　Plasma levels of soluble Fas during normal pregnancy. 　Gynecol Obstet Invest.2001 Feb;51(2):96-98. 3. Hoshimoto K, Hayashi M, Ohkura T. 　CD26 and CD30 expression on the surface of lymphocyte during normal pregnancy. 　Gynecol Obstet Invest. 2001;52(1):9-12. 4. Hoshimoto K, Mitsuya K, Ohkura T . 　Osteochondroma of the pubic symphysis associated with sexual disturbance. 　Gynecol Obstet Invest 50(1) : 70-72, 2000. 5. Hoshimoto K, Hayashi M, Ohkura T. 　Regulation of dosage of conjugated equine estrogen is useful for add- back therapy. 　J Med 31:167-175, 2000. 6. Hoshimoto K, Ohkura T. 　Vascular endothelial growth factor in human milk. 　Br J Biomed Sci 57(3) : 215-217, 2000. 7.Hoshimoto K, Hayashi M, Ohkura T. 　Mature adrenomedullin concentrations in plasma during pregnancy. 　J Matern Fetal neonatal med. 2002 Feb; 11(2) 126-9 8. Hoshimoto K, Komine F, Hayashi M, Ohkura T. 　Plasma soluble Fas changes during early pregnancy and miscarriage. 　Clin Chim Acta 2002 Sep 323 (1-2) 157-60 9. Hoshimoto K 　Changes in biomarkers for endothelial damage and hypercoagulable state 　during normal pregnancy. 　Dokkyo J Biomed Sci 2001 28 (1) 551-558 （獨協医学会　学術賞　受賞論文） 10. Hoshimoto K, Yamauchi N, Takazawa Y, Onda T, Taketani Y, Fukayama M. 　CD44 variant 6 in endometrioid carcinoma of the uterus: its expression in the adenocarcinoma component is 　an independent prognostic marker. 　Pathol Res Pract 2003;199(2):71-7
当院スタッフが研究に関わったもの
Hayashi M, Hoshimoto K, et al. Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. Eur J Haematol. 2002 Nov;69(5-6):297-302. Hayashi M, Hoshimoto K, et al. Changes in blood macrophage colony-stimulating factor levels after cesarean section in normotensive pregnancy and preeclampsia. Am J Med Sci. 2002 Jul;324(1):5-9. Hayashi M, Hoshimoto K, et al. The levels of five markers of hemostasis and endothelial status at different stages of normotensive pregnancy. Acta Obstet Gynecol Scand. 2002 Mar;81(3):208-13. Hayashi M, Hoshimoto K, et al. Successful pregnancy following gonadotropin therapy in a patient with hypogonadotropic hypogonadism resulting from craniopharyngioma. Int J Clin Pract. 2002 Mar;56(2):149-51. Hayashi M, Hoshimoto K, et al. Increased levels of macrophage colony-stimulating factor in the placenta and blood in preeclampsia. Am J Reprod Immunol. 2002 Jan;47(1):19-24. Hayashi M, Hoshimoto K, et al. Changes in urinary excretion of six biochemical parameters in normotensive pregnancy and preeclampsia. Am J Kidney Dis. 2002 Feb;39(2):392-400. Hayashi M, Hoshimoto K, et al. Increased excretion of N-acetyl-beta-D-glucosaminidase and beta2-microglobulin in gestational week 30. Am J Med Sci. 2001 Mar;321(3):168-72. Hayashi M, Hoshimoto K, et al. Primary small cell neuroendocrine carcinoma of the vagina. Marked effect of combination chemotherapy: a case report. Oncology. 2000 May;58(4):300-4. Review. Hayashi M, Hoshimoto K, et al. Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. Eur J Haematol 2002 Nov;69(5-6):297-302 Hayashi M, Hoshimoto K, et al. Successful conception following Fallopian tube recanalization in infertile patients with a unilateral proximally occluded tube and a contralateral patent tube. Hum Reprod 2003 Jan;18(1):96-9 Hayashi M, Hoshimoto K, et al. Platelet aggregation response and adenosine triphosphate secretion after abdominal total hysterectomy. Int J Clin Pract. 2003 Jul-Aug;57(6):461-6.